The move is part of a two-year commitment for the franchise to play one home game internationally for the 2018 and 2019 seasons, according to the team.
Eagles-Jaguars and Titans-Chargers will be played at Wembley Stadium.
The 2018 game overseas, like the last three, will feature the Raiders as the "home" team.
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By the end of 2018, 29 of the NFL's 32 teams will have played a game in London and the games keep getting better and better.
Since the National Football League has not yet officially issued the schedules for next season, we don't have a set time or date for the game yet. "We will play an additional game at Tottenham in a future season, over and above the planned two per year, to make up for this". While there was a ton of hype around the Raiders playing the New England Patriots in Mexico City this past season, Oakland wasn't very good and New England buzz sawed the Silver and Black.
Having staged its first National Football League game in 2007, Wembley gets its 19th and 20th games over the following two weekends.
NFL UK managing director Alistair Kirkwood told ESPN in October: "We have a desire to get the other six teams that haven't been over". They will still have all eight home games held at Lincoln Financial Field.
The Jaguars are the staple of London, having played there for five conseuctive years.
For the second season in a row, the Indianapolis Colts will be playing all 16 of their regular season games in the western hemisphere in 2018.