Other guests expected on Letterman's new six-episode Netflix series will include, George Clooney, Malala Yousafazai, Jay-Z, Tina Fey, and Howard Stern.
The booking is a huge win for Letterman and Netflix since it will be Obama's first television talk show appearance since leaving office.
Letterman, 70, who officially retired in 2015 after a 22-year run as the host of Late Show with David Letterman ― a very American melange of celebrity interviews, monologues and sketches ― had said in August that he would be back in 2018 on Netflix.
Former President Barack Obama is set to be late-night legend David Letterman's first guest on his new Netflix series next week, marking 44's return to major talk show scene.
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This would be Obama's first televised interview since his departure from the White House a year ago. The host has been off television since leaving CBS' "The Late Show" in 2015.
Comedian Stephen Colbert has since replaced Letterman on the "Late Show".
Letterman, 70, signed a deal a year ago to develop the six-episode Netflix show, for which he will be paid $2 million per episode.
"You never know when you might learn something", Letterman said of his new show. In each hour-long episode, Letterman will conduct a long-form conversation with a single guest and explore topics of his own outside the studio. "These are people that I admire".
"I got exhausted of people saying 'What do you want to do?'" Letterman told Variety in August.