Burkina Faso now occupy second place on six points, while Cape Verde, also on six points, are third.
The only previous World Cup appearance by Senegal was in 2002 when current coach Aliou Cisse captained a team that reached the quarter-finals in South Korea and Japan.
The game, which held at the Peter Mokaba Stadium in Polokwane, was a replay between the two countries after their first meeting which South Africa won 2-1 on November 12, 2016.
Nigeria and Egypt are the other two African nations to have already earned a spot at the 2018 World Cup, with the draw set to take place on December 1.
Israel downs Syrian drone over Golan
A US official who requested anonymity said the joint statement shows both leaders back a political solution and peace process. In September, Israel shot down an Iranian-made drone, sent by the Lebanese militant group Hezbollah, in the same area.
Baxter, addressing reporters shortly after his team suffered a 2-0 deficit in the hands of Senegal, which ended their World Cup hopes, said both the Super Eagles and the Taranga Lions are inferior to his side.
"We are going to represent all of Africa in Russian Federation next year and will do our best to make everyone proud".
The visitors are now five points ahead of nearest Group D challengers Burkina Faso with one game remaining.
However, leading up to the game, the South African camp has been hit with a series of suspension and injury problems, including Khune, who fractured a bone in his face in a Telkom Knockout match last weekend.
Goalkeeper Khadim Ndiaye failed to grasp a fierce close-range Themba Zwane shot, but recovered to catch the rebound after the ball struck the onrushing Percy Tau. Sadio Mané played Sakho through on goal with a defence-splitting pass and the West Ham striker slotted the ball past Khune. Khune's outstretched leg denied the Liverpool frontman, but the ball ricocheted off Mkhize and into the net.