Duterte was referring to Representatives Randy Hultgren of IL and James McGovern of MA, co-chairmen of the Tom Lantos Human Rights Commission, who had urged US President Donald Trump to "impress upon President Duterte the United States" profound concern over reported extra-judicial killings associated with the Philippine government's "war on drugs'" during their meeting in Manila next week.
"I was just 16 years old then, and it was just over a look", he added, referring to what caused him to stab the person.
"How much more now that I am president?"
The Filipino president has faced severe criticism for endorsing extrajudicial mass killings, imprisoning his critics and threatening to kill whoever raised their voice against his government.
A spokesman for Duterte said the remarks had been made "in jest".
Duterte is in Vietnam for the Asia-Pacific Economic Cooperation (APEC) Summit, before returning to the Philippines to host world leaders in the 31st Association of Southeast Asian Nations (ASEAN) Summit and related meetings with its dialogue partners.
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But the Philippine president appeared to be dead serious. "Never mind about the human rights advocates".
Senate Majority leader Vicente Sotto 3rd on Friday also slammed the two USA lawmakers for meddling in the Philippine government's anti-illegal drugs campaign.
Perhaps that is why Duterte didn't hesitate warning his US counterpart to "lay off" on human rights questions when they finally meet in Manila.
"If you do not like me, I do not like you. I take care of my country and I will nurture my country to health". "We're even", he said without naming any names.
Thursday was not even the first time he has mentioned stabbing and killing someone while a teenager.
"Sabihin ko sa kanila, you are too presumptuous".